May have been damage to the PIC resulting from a mishap with a breadboard 'lashup' (Ian.M)
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#Genius g540 programmer serial
Also the UART tool and serial EEPROMS are not (yet) supported. Head" Many of these objections have been removed by the introduction of the standalone PICkit 3 Scripting tool which adds a PICkit 2 emulation mode, unfortunately with the same limited device support.
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The remaining official support life is uncertain. The PICkit 2 is even supported in MPLAB X.